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	<title>BIOIPR &#187; 术语百汇-生物科技</title>
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	<description>生物技术&#38;中欧知识产权 Biotech &#38; EU-China IPR</description>
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		<title>Tissue Factor&#124;Thromboplastin &#124; 组织因子</title>
		<link>http://www.bioipr.com/lexis/531/</link>
		<comments>http://www.bioipr.com/lexis/531/#comments</comments>
		<pubDate>Fri, 11 Mar 2011 11:42:55 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[组织因子



是一个由263 个氨基酸残基组成的跨膜单链糖蛋白,分子量约为47 kDa。其中氨基端219 个氨基酸残基位于细胞膜外,紧随其后的23 个氨基酸残基则穿过细胞膜,其余21 个氨基酸残基位于细胞质内。正常情况下,组织因子位于血管壁外膜细胞,包绕血管的成纤维细胞,肝、脾、肾等器官的纤维囊,及皮肤外层的表皮细胞、肾小球上皮细胞、脑皮质、心肌细胞、肺泡巨噬细胞、胃肠道壁、部分生殖泌尿道和子宫内膜基质细胞中,而在血管中膜或内膜层却很稀少。因此在正常情况下组织因子不存在于循环中或不与循环血液接触,只有当血管壁的完整性遭到破坏时TF 才暴露于循环血液,通过激活凝固级联反应发挥止血作用。

<span class="readmore"><a href="http://www.bioipr.com/lexis/531/" title="Tissue Factor&#124;Thromboplastin &#124; 组织因子">Read More: 1762 Words Totally</a></span> <a href="http://www.bioipr.com/lexis/531/" rel="bookmark">more</a>]]></description>
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		<title>Shiga toxins&#124;Shiga-Toxine&#124;志贺毒素</title>
		<link>http://www.bioipr.com/lexis/478/</link>
		<comments>http://www.bioipr.com/lexis/478/#comments</comments>
		<pubDate>Mon, 15 Nov 2010 22:11:01 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[志贺毒素(Shiga toxin,Stxs)是大肠杆菌O157的主要毒力因子之一,有两个生物型:Stx1和Stx2,只产生Stx2的菌株毒力比只分泌Stx1和两者同时 分泌的菌株毒力都强。Stx2致病剂量极低,且分泌胞外,Stx2的检测将直接有助于对分离菌株致病力强弱的判定,提高对高致病性大肠杆菌O157菌株的 检出。 &#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;英文解释&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595; Shiga toxins are a family of related toxins with two major groups, Stx1 and Stx2, whose genes are considered to be part of the genome of lambdoid prophages.[1] The toxins are named for Kiyoshi Shiga, who first described the bacterial origin of dysentery caused by Shigella dysenteriae. The most common sources for Shiga toxin are the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli (STEC), which includes serotype O157:H7 and other enterohemorrhagic E. coli (EHEC).[2] &#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;德文解释&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595;&#8595; Shiga-Toxine hei&#223;en zwei nach dem japanischen Bakteriologen Kiyoshi Shiga benannte cytotoxische Proteine, produziert von Shigella dysenteriae, dem Erreger der Shigellosen oder Bakterienruhr. Bei Shigatoxin B handelt es sich um ein Membrantransport-Protein, und Shigatoxin A ist ein Enzym, das die Verst&#252;mmelung der ribosomalen RNA katalysiert. Mittlerweile existieren auch bereits St&#228;mme von Escherichia coli, die diese Toxine produzieren. Das Gesamt-Shiga-Toxin besteht aus zwei Untereinheiten, die &#252;ber Disulfidbr&#252;cken miteinander verbunden sind. Die B-Untereinheit (7,6&#160;kDa) ist f&#252;nffach vorhanden und sorgt f&#252;r die Bindung an die Zelloberfl&#228;che und daf&#252;r, dass die A-Untereinheit in das Zellinnere geschleust wird, wo diese die Proteinsynthese durch Spaltung der 28s-rRNA hemmt. Es besitzt einen ausgepr&#228;gten Neurotropismus. Shiga-Toxine z&#228;hlen zu den Lektinen. Sie sind keine Enterotoxine und nicht f&#252;r den Durchfall bei Shigellose verantwortlich, sondern f&#252;r deren h&#228;molytischen Verlauf. http://en.wikipedia.org/wiki/Shiga_toxin _______________________________________ From Wikipedia, the free encyclopedia &#183; Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation;with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts.A copy of the license is included in the section entitled &#8220;GNU Free Documentation License&#8221;.

<span class="readmore"><a href="http://www.bioipr.com/lexis/478/" title="Shiga toxins&#124;Shiga-Toxine&#124;志贺毒素">Read More: 2108 Words Totally</a></span> <a href="http://www.bioipr.com/lexis/478/" rel="bookmark">more</a>]]></description>
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		<title>Polyethylene glycol｜聚乙二醇</title>
		<link>http://www.bioipr.com/lexis/448/</link>
		<comments>http://www.bioipr.com/lexis/448/#comments</comments>
		<pubDate>Fri, 17 Sep 2010 09:55:07 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[聚乙二醇（PEG），也稱為聚(環氧乙烯)（PEO）或聚氧乙烯（POE），是指環氧乙烷的寡聚物或聚合物。這三個名稱現今一般為同義詞，但歷史上聚乙二醇往往是指分子質量低於20,000 g/mol的低聚物和聚合物，PEO是指分子量超過20,000的聚合物，POE則可指任何分子質量的聚合物。

聚乙二醇溶於水、甲醇、苯、二氯甲烷，不溶於乙醚和正己烷。它與疏水性分子結合後的產物可用作非離子表面活性劑。

聚乙二醇可以用於修飾藥物蛋白，以保護藥物分子延長其作用半衰期。

<span class="readmore"><a href="http://www.bioipr.com/lexis/448/" title="Polyethylene glycol｜聚乙二醇">Read More: 3164 Words Totally</a></span> <a href="http://www.bioipr.com/lexis/448/" rel="bookmark">more</a>]]></description>
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		<title>Angiogenesis&#124;Angiogenese&#124;血管新生</title>
		<link>http://www.bioipr.com/lexis/434/</link>
		<comments>http://www.bioipr.com/lexis/434/#comments</comments>
		<pubDate>Mon, 06 Sep 2010 11:29:28 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[血管新生（英文：Angiogenesis）是一个生理上新的微血管發展成一個血流供應系統的過程。 <a href="http://www.bioipr.com/lexis/434/" rel="bookmark">more</a>]]></description>
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		<title>Proteopathy &#124; protein conformational diseases &#124; 蛋白质构象疾病</title>
		<link>http://www.bioipr.com/lexis/332/</link>
		<comments>http://www.bioipr.com/lexis/332/#comments</comments>
		<pubDate>Thu, 18 Dec 2008 14:36:23 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[简单地讲，蛋白质构象病就是指蛋白质三维结构出现错乱（错误折叠），而致使蛋白质三维结构所应表达的功能出现错乱，使其丧失其生物学功能而带来的疾病。 <a href="http://www.bioipr.com/lexis/332/" rel="bookmark">more</a>]]></description>
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		<title>epitope &#124; 抗原决定簇</title>
		<link>http://www.bioipr.com/lexis/330/</link>
		<comments>http://www.bioipr.com/lexis/330/#comments</comments>
		<pubDate>Tue, 09 Dec 2008 16:04:38 +0000</pubDate>
		<dc:creator>Zhuomin Wu</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[Epitope是决定抗原性的特殊化学基团。大多存在于抗原物质的表面，有些存在于抗原物质的内部，须经酶或其他方式处理后才暴露出来。 <a href="http://www.bioipr.com/lexis/330/" rel="bookmark">more</a>]]></description>
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		<title>cytoplasm/ Zytoplasma/ 细胞质</title>
		<link>http://www.bioipr.com/lexis/316/</link>
		<comments>http://www.bioipr.com/lexis/316/#comments</comments>
		<pubDate>Tue, 28 Oct 2008 09:56:04 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[cytoplasm/ Zytoplasma/ 细胞质中文、英文、德文解释 <a href="http://www.bioipr.com/lexis/316/" rel="bookmark">more</a>]]></description>
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		<title>Fusion Protein &#124; 融合蛋白质</title>
		<link>http://www.bioipr.com/lexis/186/</link>
		<comments>http://www.bioipr.com/lexis/186/#comments</comments>
		<pubDate>Wed, 27 Aug 2008 14:08:53 +0000</pubDate>
		<dc:creator>武卓敏</dc:creator>
				<category><![CDATA[术语百汇-生物科技]]></category>

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		<description><![CDATA[&#160;

↓↓↓↓↓↓↓↓↓↓中文解释↓↓↓↓↓↓↓↓↓↓

融合蛋白

<span class="readmore"><a href="http://www.bioipr.com/lexis/186/" title="Fusion Protein &#124; 融合蛋白质">Read More: 1522 Words Totally</a></span> <a href="http://www.bioipr.com/lexis/186/" rel="bookmark">more</a>]]></description>
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